Kitasamycin (INN) is a macrolide antibiotic. It is produced by Streptomyces kitasatoensis.[1] The drug has antimicrobial activity against a wide spectrum of pathogens. There are several generic names of this drug such as:[2]
- Kitasamycin (OS: BAN, JAN, USAN)
- Kitasamycine (OS: DCF)
- C 637 (IS)
- Katasamycin (IS)
- Leucomycin (IS)
- Kitasamycin (PH: JP XV)
- Kitasamycin Acetate (OS: JAN)
- Leucomycin Acetate (IS)
- Kitasamycin Acetate (PH: JP XV)
- Kitasamycin Tartrate (OS: JAN)
- Leucomycin Tartrate (IS)
- Kitasamycin Tartrate (PH: JP XV)
Quick Facts Clinical data, Other names ...
Kitasamycin |
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Other names | Turimycin |
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AHFS/Drugs.com | International Drug Names |
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ATCvet code | |
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[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name)
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ChEMBL | |
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Formula | C35H59NO13 |
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Molar mass | 701.851 g·mol−1 |
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3D model (JSmol) | |
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C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O
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InChI=1S/C35H59NO13/c1-19-16-23(14-15-37)31(32(44-8)25(39)17-26(40)45-20(2)12-10-9-11-13-24(19)38)49-34-29(41)28(36(6)7)30(21(3)47-34)48-27-18-35(5,43)33(42)22(4)46-27/h9-11,13,15,19-25,27-34,38-39,41-43H,12,14,16-18H2,1-8H3/b10-9+,13-11+/t19-,20-,21-,22+,23+,24+,25-,27+,28-,29-,30-,31+,32+,33+,34+,35-/m1/s1 NKey:XYJOGTQLTFNMQG-KJHBSLKPSA-N N
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Zheng Q, Gao S (November 2016). "The effect of surfactant on fermentation of kitasamycin in Streptomyces kitasatoensis". Biotechnology and Applied Biochemistry. 63 (6): 895–900. doi:10.1002/bab.1443. PMID 26339801. S2CID 7290695.