Lipstatin
Chemical compound / From Wikipedia, the free encyclopedia
Lipstatin is a potent, irreversible inhibitor of pancreatic lipase. It is a natural product that was first isolated from the actinobacterium Streptomyces toxytricini.[1]
Quick Facts Names, Identifiers ...
Names | |
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Systematic IUPAC name
(2S,4Z,7Z)-1-[(2S,3S)-3-Hexyl-4-oxooxetan-2-yl]trideca-4,7-dien-2-yl (2S)-2-formamido-4-methylpentanoate | |
Other names
(2S,4Z,7Z)-1-[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]-4,7-tridecadien-2-yl N-formyl-L-leucinate | |
Identifiers | |
3D model (JSmol) |
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ChemSpider |
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ECHA InfoCard | 100.126.007 |
MeSH | Lipstatin |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C29H49NO5 | |
Molar mass | 491.713 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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The popular antiobesity drug orlistat (trade names Xenical and alli) is a saturated derivative of lipstatin.