Lynestrenol
Androgen and anabolic steroid / From Wikipedia, the free encyclopedia
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Lynestrenol, sold under the brand names Exluton and Ministat among others, is a progestin medication which is used in birth control pills and in the treatment of gynecological disorders.[2][3][4] The medication is available both alone and in combination with an estrogen.[3][5][6] It is taken by mouth.[7][8]
Clinical data | |
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Trade names | Exluton, Ministat, others |
Other names | Linestrenol; Lynenol;[1] NSC-37725; 17α-Ethynylestr-4-en-17β-ol; 19-Nor-17α-pregn-4-en-20-yn-17-ol[1] |
AHFS/Drugs.com | International Drug Names |
Routes of administration | By mouth |
Drug class | Progestogen; Progestin |
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ECHA InfoCard | 100.000.139 |
Chemical and physical data | |
Formula | C20H28O |
Molar mass | 284.443 g·mol−1 |
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Lynestrenol is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone.[9] It has weak androgenic and estrogenic activity and no other important hormonal activity.[9][10] The medication is a prodrug of norethisterone in the body, with etynodiol occurring as an intermediate.[10][11][12]
Lynestrenol was discovered in the late 1950s and was introduced for medical use in 1961.[13][14] It has mostly been used in Europe and elsewhere in the world and was never marketed in the United States.[6][15][16][17]