MT-ND5
Mitochondrial gene coding for a protein involved in the respiratory chain / From Wikipedia, the free encyclopedia
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MT-ND5 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 5 protein (ND5).[5] The ND5 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.[6] Variations in human MT-ND5 are associated with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) as well as some symptoms of Leigh's syndrome and Leber's hereditary optic neuropathy (LHON).[7][8]
Quick Facts ND5, Identifiers ...
ND5 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | ND5, mitochondrially encoded NADH dehydrogenase 5, MTNADH dehydrogenase, subunit 5 (complex I), NADH dehydrogenase subunit 5 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 516005 MGI: 102496 HomoloGene: 36212 GeneCards: ND5 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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