Malonate decarboxylase holo-(acyl-carrier protein) synthase

Malonate decarboxylase holo-(acyl-carrier protein) synthase (EC 2.7.7.66, holo ACP synthase, '2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo ACP 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA transferase, MdcG, 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase adenylyltransferase, holo-malonate-decarboxylase synthase) is an enzyme with systematic name 2'-(5-triphosphoribosyl)-3'-dephospho-CoA:apo-malonate-decarboxylase 2'-(5-phosphoribosyl)-3'-dephospho-CoA-transferase .^[1][2] This enzyme catalyses the following chemical reaction

2'-(5-triphosphoribosyl)-3'-dephospho-CoA + malonate decarboxylase apo-[acyl-carrier protein] ${\displaystyle \rightleftharpoons }$ malonate decarboxylase holo-[acyl-carrier protein] + diphosphate

Malonate decarboxylase holo-(acyl-carrier protein) synthase
Identifiers
EC no.	2.7.7.66
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The delta subunit of malonate decarboxylase serves as an acyl-carrier protein (ACP) .

References

1. Hoenke S, Wild MR, Dimroth P (October 2000). "Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase". Biochemistry. 39 (43): 13223–32. doi:10.1021/bi0011532. PMID 11052675.
2. Hoenke S, Schmid M, Dimroth P (October 2000). "Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases". Biochemistry. 39 (43): 13233–40. doi:10.1021/bi001154u. PMID 11052676.

External links

• Malonate+decarboxylase+holo-(acyl-carrier+protein)+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)^{[dead link]}