Mitochondrial biogenesis
Process by which cells build mitochondrial mass / From Wikipedia, the free encyclopedia
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Mitochondrial biogenesis is the process by which cells increase mitochondrial numbers.[1][2] It was first described by John Holloszy in the 1960s, when it was discovered that physical endurance training induced higher mitochondrial content levels, leading to greater glucose uptake by muscles.[3] Mitochondrial biogenesis is activated by numerous different signals during times of cellular stress or in response to environmental stimuli, such as aerobic exercise.[1][2][4]