DNA polymerase subunit gamma-2, mitochondrial is a protein that in humans is encoded by the POLG2 gene. The POLG2 gene encodes a 55 kDa accessory subunit protein that imparts high processivity and salt tolerance to the catalytic subunit of DNA polymerase gamma, encoded by the POLG gene.[5][6] Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[7]
Quick Facts Available structures, PDB ...
POLG2 |
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Identifiers |
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Aliases | POLG2, HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB, polymerase (DNA) gamma 2, accessory subunit, DNA polymerase gamma 2, accessory subunit, MTDPS16, MTDPS16A, MTDPS16B |
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External IDs | OMIM: 604983 MGI: 1354947 HomoloGene: 5221 GeneCards: POLG2 |
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Wikidata |
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