Phantasmidine
Chemical compound / From Wikipedia, the free encyclopedia
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Phantasmidine is a toxic substance derived from the Ecuadorian poisonous frog Anthony's poison arrow frog (Epipedobates anthonyi), more commonly known as the “phantasmal poison frog”.[2] It is a nicotinic agonist, meaning it binds to nicotinic receptors in the body and mimics the effects of the neurotransmitter acetylcholine. This causes the stimulation of the body's parasympathetic nervous system, which induces many inhibitory behaviors in the body such as decreased heart rate.
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Preferred IUPAC name
(2aS,4aR,9aR)-7-Chloro-1,2,2a,3,4,4a-hexahydrocyclobuta[4′,5′]pyrrolo[3′,4′:4,5]furo[2,3-b]pyridine | |
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Properties[1] | |
C11H11ClN2O | |
Molar mass | 222.67 g·mol−1 |
Appearance | Crystalline solid |
Density | 1.5±0.1 g/cm3 |
Boiling point | 358.9±42.0°C at 760 mmHg |
Hazards | |
Flash point | 170.9±27.9°C |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Phantasmidine is characterized in the same class as epibatidine, which is a similar nicotinic acetylcholine agonist derived from a poisonous frog species. Some synthetic processes can even generate phantasmidine using epibatidine as a starting reagent. Epibatidine and epibatidine-related compounds have an LD50 of around 4 µg in mice;[3] however, the exact LD50 of phantasmidine is not known.
Phantasmidine may find application as an analgesic or muscle relaxant.