Phosalacine
Chemical compound / From Wikipedia, the free encyclopedia
Phosalacine is a natural antimicrobial and herbicidal compound that has been isolated from the Actinobacteria Kitasatosporia phosalacinea.[1]
Quick Facts Names, Identifiers ...
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IUPAC name
(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl]amino]propanoyl]amino]-4-methylpentanoic acid | |
Other names
(2S)-2-Amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-leucine | |
Identifiers | |
3D model (JSmol) |
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Properties | |
C14H28N3O6P | |
Molar mass | 365.367 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It is a tripeptide consisting of the amino acids glufosinate (phosphinothricin), alanine, and leucine.[2] It is similar in structure to bialaphos, differing by replacement of the terminal alanine with leucine.
Phosalacine has antimicrobial activity against Gram-positive and Gram-negative bacteria and some fungi.[1] It also shows herbicidal activity against alfalfa.[1] It is believed that the herbicidal activity is due to the slow release of glufosinate,[3] which is a commercially-used broad spectrum herbicide.