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Class of enzymes that cleave phospholipids From Wikipedia, the free encyclopedia
A phospholipase is an enzyme that hydrolyzes phospholipids[1] into fatty acids and other lipophilic substances. There are four major classes, termed A, B, C, and D, which are distinguished by the type of reaction which they catalyze:
Types C and D are considered phosphodiesterases.
Endothelial lipase is primarily a phospholipase.[2]
Phospholipase A2 acts on the intact lecithin molecule and hydrolyzes the fatty acid esterified to the second carbon atom. The resulting products are lysolecithin and a fatty acid. Phospholipase A2 is an enzyme present in the venom of bees, blennies and viper snakes.[3]
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