Prednylidene
Chemical compound / From Wikipedia, the free encyclopedia
Prednylidene is a glucocorticoid[1] for systemic use.
Quick Facts Clinical data, Other names ...
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Other names | (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-one |
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ECHA InfoCard | 100.009.060 |
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Formula | C22H28O5 |
Molar mass | 372.461 g·mol−1 |
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Substitution at position 16 also leads to more potent corticosteroids. The additional steric bulk introduced by such substituents adjacent to the dihydroxyacetone side chain also protects that moiety against metabolic degradation.