Prepilin peptidase
Enzyme responsible for maturing type 4 pilins / From Wikipedia, the free encyclopedia
Prepilin peptidase (EC 3.4.23.43) is an enzyme found in Type IV filament systems responsible for the maturation of the pilin.[1][2] This enzyme catalyses the following chemical reaction
- Typically cleaves a -Gly-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.
Quick Facts Identifiers, EC no. ...
Prepilin peptidase | |||||||||
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Identifiers | |||||||||
EC no. | 3.4.23.43 | ||||||||
CAS no. | 202833-59-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Quick Facts Type IV leader peptidase family (A24), Identifiers ...
Type IV leader peptidase family (A24) | |||||||||
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Identifiers | |||||||||
Symbol | Peptidase_A24 | ||||||||
Pfam | PF01478 | ||||||||
InterPro | IPR000045 | ||||||||
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This enzyme is present on the surface of many species of bacteria. All known enzymes with this activity are of the MEROPS family A24.