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Chemical compound From Wikipedia, the free encyclopedia
RH-34 is a compound which acts as a potent and selective partial agonist for the 5-HT2A serotonin receptor subtype. It was derived by structural modification of the selective 5-HT2A antagonist ketanserin, with the 4-(p-fluorobenzoyl)piperidine moiety replaced by the N-(2-methoxybenzyl) pharmacophore found in such potent 5-HT2A agonists as NBOMe-2C-B and NBOMe-2C-I. This alteration was found to retain 5-HT2A affinity and selectivity, but reversed activity from an antagonist to a moderate efficacy partial agonist.[2][3][4]
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Formula | C18H19N3O3 |
Molar mass | 325.368 g·mol−1 |
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RH-34 is a controlled substance in Hungary[5] and Brazil.[6]
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