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American dermatologist (born 1958) From Wikipedia, the free encyclopedia
Richard L. Gallo is an American dermatologist who is a Distinguished Professor and founding Chairman of Dermatology at the University of California, San Diego. His research accomplishments as a physician-scientist include discovery of antimicrobial peptides in mammalian skin, establishing new links between innate immunity and skin diseases such as atopic dermatitis and rosacea, and defining the functions of the skin microbiome in host immune defense.
Richard L. Gallo | |
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Born | United States | December 9, 1958
Occupation(s) | Professor, Dermatologist |
Known for | Antimicrobial Peptides, Microbiome |
Gallo did his undergraduate studies at the University of Chicago, earned his MD and PhD at the University of Rochester, interned in Pediatrics at Johns Hopkins Hospital, was a Dermatology resident at Harvard Medical School and was a postdoctoral fellow at Harvard University under the supervision of Merton Bernfield'
Gallo studies how humans interact with the environment and protect themselves from infection. He discovered that antimicrobial peptides are present in mammalian skin by demonstrating that cathelicidin antimicrobial peptides(Cathelicidins) are present during wound repair.[1] Subsequent work from his laboratory used molecular techniques to produce a knock out mouse that has shown how cathelicidin antimicrobials protect against infection in several organs including the skin.[2] By using a wide variety of biochemical and genetic tools his work has also shown that other antimicrobial peptides and elements of innate immunity such as Toll-like receptors and Hyaluronan influence human health. His work has translated into a new understanding of the cause of rosacea, a finding with immediate therapeutic implications. Most recently his research has defined biochemical mechanisms through which Vitamin D and the normal skin microflora Microbiome can control immune responses. These latest findings have advanced understanding of the Hygiene hypothesis, Atopic Dermatitis and Rosacea. His analysis of the function of the human skin microbiome is leading discovery of new therapeutic approaches to disease by discovering molecules from bacteria on the skin that can be used for drugs.
Several press releases and scientific publications have reported his discoveries.[3][4][5][6][7][8][9][10]
This section of a biography of a living person does not include any references or sources. (July 2023) |
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