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Monoclonal antibody From Wikipedia, the free encyclopedia
Rilotumumab (previously AMG102) is a human monoclonal antibody designed for the treatment of solid tumors.[1]
Monoclonal antibody | |
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Type | Whole antibody |
Source | Human |
Target | HGF |
Clinical data | |
ATC code |
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Identifiers | |
CAS Number | |
ChemSpider |
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Chemical and physical data | |
Formula | C6464H9932N1708O2010S46 |
Molar mass | 145207.27 g·mol−1 |
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Rilotumumab was in development by Amgen, Inc. until in November 2014, when Amgen announced it had halted all clinical trials of the compound in advanced gastric cancer (including two Phase III studies) after one of the trials found an increase in the number of deaths in those who were taking rilotumumab and chemotherapy when compared to those who were only administered chemotherapy.[2][3]
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