Rilpivirine
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Rilpivirine, sold under the brand names Edurant and Rekambys, is a medication, developed by Tibotec, used for the treatment of HIV/AIDS.[5][6] It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs such as efavirenz.[7][8]
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Edurant, Rekambys |
Other names | TMC278 |
AHFS/Drugs.com | Monograph |
MedlinePlus | a611037 |
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Routes of administration | By mouth, intramuscular |
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Pharmacokinetic data | |
Protein binding | 99.7% |
Metabolism | CYP3A4 |
Elimination half-life | tablets: 45 hours injection: 13–28 weeks |
Excretion | 85% via faeces, 6% via urine |
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ECHA InfoCard | 100.224.394 |
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Formula | C22H18N6 |
Molar mass | 366.428 g·mol−1 |
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