SCH-79687

SCH-79687 is a histamine antagonist selective for the H₃ subtype.^[1]

SCH-79687

Names
Preferred IUPAC name N-(3,5-Dichlorophenyl)-N′-({4-[(1H-imidazol-4-yl)methyl]phenyl}methyl)urea
Identifiers
CAS Number	224585-45-9 N
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL366977 Y
ChemSpider	7977505 Y
PubChem CID	9801743
UNII	YF792N2EXV Y
CompTox Dashboard (EPA)	DTXSID20430941
InChI InChI=1S/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) Y Key: CXNCQFJNXQAFND-UHFFFAOYSA-N Y InChI=1/C18H16Cl2N4O/c19-14-6-15(20)8-16(7-14)24-18(25)22-9-13-3-1-12(2-4-13)5-17-10-21-11-23-17/h1-4,6-8,10-11H,5,9H2,(H,21,23)(H2,22,24,25) Key: CXNCQFJNXQAFND-UHFFFAOYAC
SMILES Clc1cc(cc(Cl)c1)NC(=O)NCc2ccc(cc2)Cc3c[nH]cn3
Properties
Chemical formula	C18H16Cl2N4O
Molar mass	375.251 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

References

1. McLeod RL, Rizzo CA, West RE Jr, Aslanian R, McCormick K, Bryant M, Hsieh Y, Korfmacher W, Mingo GG, Varty L, Williams SM, Shih NY, Egan RW, Hey JA. Pharmacological characterization of the novel histamine H3-receptor antagonist N-(3,5-dichlorophenyl)-N'-[[4-(1H-imidazol-4-ylmethyl)phenyl]-methyl]-urea (SCH 79687). Journal of Pharmacology and Experimental Therapeutics. 2003 Jun;305(3):1037-44. PMID 12649305 doi=10.1124/jpet.103.049254