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Medical condition From Wikipedia, the free encyclopedia
The shoulder pad sign is an enlargement of the anterior shoulder due to amyloid deposition in periarticular soft tissue.[1][2][3] This type of infiltration is not common, but it is pathognomonic for AL amyloidosis.[1][2][3]
Shoulder pad sign | |
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Shoulder pad sign | |
Differential diagnosis | AL amyloidosis |
Analysis of the amyloid protein has demonstrated that it has a kappa III Ig light chain structure.[1] The variable region of kappa III amyloid proteins may show an increased likelihood of depositing in soft tissue.[1]
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