Subtilisin
Proteolytic enzyme found in Bacillus subtilis / From Wikipedia, the free encyclopedia
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Subtilisin is a protease (a protein-digesting enzyme) initially obtained from Bacillus subtilis.[2][3][4][5][6][7][8]
Quick Facts Peptidase S8, subtilisin-related, Identifiers ...
Peptidase S8, subtilisin-related | |||||||||
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Identifiers | |||||||||
Symbol | Peptidase_S8 | ||||||||
Pfam | PF00082 | ||||||||
InterPro | IPR015500 | ||||||||
PROSITE | PDOC00125 | ||||||||
CATH | 1cse | ||||||||
SCOP2 | 1cse / SCOPe / SUPFAM | ||||||||
CDD | cd07477 | ||||||||
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Quick Facts Identifiers, Organism ...
Subtilisin BPN' | |||||||
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Identifiers | |||||||
Organism | Bacillus amyloliquefaciens | ||||||
Symbol | apr | ||||||
CAS number | 9014-01-1 | ||||||
Entrez | 5712479 | ||||||
PDB | 1st2 More structures | ||||||
UniProt | P00782 | ||||||
Other data | |||||||
EC number | 3.4.21.62 | ||||||
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GO:0004252 |
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Subtilisins belong to subtilases, a group of serine proteases that – like all serine proteases – initiate the nucleophilic attack on the peptide (amide) bond through a serine residue at the active site. Subtilisins typically have molecular weights 27kDa. They can be obtained from certain types of soil bacteria, for example, Bacillus amyloliquefaciens from which they are secreted in large amounts.