Swainsonine
Chemical compound / From Wikipedia, the free encyclopedia
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Swainsonine is an indolizidine alkaloid. It is a potent inhibitor of Golgi alpha-mannosidase II, an immunomodulator, and a potential chemotherapy drug.[1] As a toxin in locoweed (likely its primary toxin[2]) it also is a significant cause of economic losses in livestock industries, particularly in North America. It was first isolated from Swainsona canescens.[3]
This article may be too technical for most readers to understand. (January 2022) |
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
(1S,2R,8R,8aR)-Octahydroindolizine-1,2,8-triol | |
Other names
Tridolgosir | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.123.531 |
KEGG |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C8H15NO3 | |
Molar mass | 173.2 |
Melting point | 143 to 144 °C (289 to 291 °F; 416 to 417 K) |
10 mg/1 mL | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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