TRPV
Subgroup of TRP cation channels named after the vanilloid receptor / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about TRPV?
Summarize this article for a 10 year old
TRPV is a family of transient receptor potential cation channels (TRP channels) in animals. All TRPVs are highly calcium selective.
Transient receptor potential (TRP) ion channel | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
Symbol | TRP | ||||||||
Pfam | PF06011 | ||||||||
InterPro | IPR010308 | ||||||||
|
TRP channels are a large group of ion channels consisting of six protein families, located mostly on the plasma membrane of numerous human and animal cell types, and in some fungi.[2] TRP channels were initially discovered in the trp mutant strain of the fruit fly Drosophila [3] that displayed transient elevation of potential in response to light stimuli, and were therefore named "transient receptor potential" channels.[4] The name now refers only to a family of proteins with similar structure and function, not to the mechanism of their activation. Later, TRP channels were found in vertebrates where they are ubiquitously expressed in many cell types and tissues. There are about 28 TRP channels that share some structural similarity to each other.[5] These are grouped into two broad groups: group 1 includes TRPC ( "C" for canonical), TRPV ("V" for vanilloid), TRPM ("M" for melastatin), TRPN and TRPA. In group 2 there are TRPP ("P" for polycystic) and TRPML ("ML" for mucolipin).