- 17 March 599 coincided with Thirteenth of Rajab, 24 BH: Birth of Ali ibn Abi Talib in the Ka'ba, in the city of Mecca.
- 610: Ali converted to Islam soon before the first revelation of the Quran.
- 613: Yawm al-Inzar: Muhammad invited the Banu Hashim to Islam; Ali alone accepted his call.
- 617- 619: Meccan boycott of the Hashemites[1]
- 619:Year of Sorrow:Death of Abu Talib, Ali's father.[1]
- September 622: Laylat al-mabit: Ali risked his life by sleeping in Muhammad's bed to impersonate him and thwart an assassination plot, so that Muhammad could escape from Mecca in safety and migrate to Medina.[1]
- 622: Ali migrated with his wife, Fatima Zahra and Umm Kulthum bint Ali, and another women.
- 622 or 623:The prophet chose him as his brother.[2]
- 623: Ali married with Fatima Zahra, Muhammad's daughter.[3]
- 624
- March 17: Battle of Badr: Ali first distinguished himself as a warrior and killed about 20 to 22 pagans.
- Expulsion of the Bani Qainuqa Jews from Medina.[1]
- 625:
- Birth of Hasan ibn Ali, the second Shia Imam.
- Battle of Uhud: Ali destroyed the standard bearers and when the army of Islam was defeated and most of the Muslims had fled Ali was one of the few Muslims who defended Muhammad.
- Expulsion of Banu Nadir Jews from Medina.[1]
- 626:
- 627
- 628
- 629
- 630
- 631
- 632
- 644: Umar, the second Rashidun caliph, was assassinated. Ali was one of the electoral council to choose the third caliph
- 648: Birth of Al-Abbas ibn Ali
- 656:
- 657:Ali shifted the capital of Rashidun empire from Medina to Kufa in Iraq.[1]
- May–July 657: Battle of Siffin[4]
- 658:
- 659:
- 660:
- 28 January 661 coincided with Twenty-first of Ramadan: Ali dead in Kufa and buried in Najaf two days after he was struck by Abd-al-Rahman ibn Muljam in the Great Mosque of Kufa.