Topical hydrocortisone
Pharmaceutical drug / From Wikipedia, the free encyclopedia
Topical hydrocortisone is a drug under the class of corticosteroids, which is used for the treatment of skin inflammation, itchiness and allergies.[10] Some examples include insect bites, dermatitis and rash.[11][12][13]
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Trade names | Ala-Cort, Aquanil HC, Beta HC, others [1] |
Other names | Cortisol; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682793 |
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Routes of administration | Topical |
Drug class | Corticosteroid; Glucocorticoid; Mineralocorticoid |
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Formula | C21H30O5 |
Molar mass | 362.466 g·mol−1 |
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Hydrocortisone was discovered by Nobel laureates Edward C. Kendall and Philip S. Hench in the 1930s while they were conducting research on rheumatoid arthritis.[14][15][16] Its topical use was first recorded in the 1950s.[17][18]
The most common adverse effects after the application of topical hydrocortisone are burning and stinging sensations.[10][11] Side effects after long-term usage include eyesight damage, elevated blood sugar levels and adrenal gland disorders.[12]
Topical hydrocortisone is available in several dosage forms such as solution, lotion, cream, ointment and spray.[19] Some brand names for topical hydrocortisone include Anusol HC, Cortizone 10, and Synacort.[19]