Toxic shock syndrome toxin-1
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Toxic shock syndrome toxin-1 (TSST-1) is a superantigen with a size of 22 kDa[1] produced by 5 to 25% of Staphylococcus aureus isolates. It causes toxic shock syndrome (TSS) by stimulating the release of large amounts of interleukin-1, interleukin-2 and tumour necrosis factor. In general, the toxin is not produced by bacteria growing in the blood; rather, it is produced at the local site of an infection, and then enters the blood stream.
Quick Facts Identifiers, Organism ...
Toxic shock syndrome toxin-1 | |||||||
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Identifiers | |||||||
Organism | Staphylococcus aureus | ||||||
Symbol | tst | ||||||
PDB | 3TSS | ||||||
RefSeq (Prot) | WP_001035596.1 | ||||||
UniProt | P06886 | ||||||
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