Type I site-specific deoxyribonuclease
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Type I site-specific deoxyribonuclease (EC 3.1.21.3, type I restriction enzyme, deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent), restriction-modification system, deoxyribonuclease (adenosine triphosphate-hydrolyzing), adenosine triphosphate-dependent deoxyribonuclease, ATP-dependent DNase, type 1 site-specific deoxyribonuclease) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolysed
Quick Facts Identifiers, EC no. ...
Type I site-specific deoxyribonuclease | |||||||||
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Identifiers | |||||||||
EC no. | 3.1.21.3 | ||||||||
CAS no. | 37263-09-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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They have an absolute requirement for ATP (or dATP) and S-adenosyl-L-methionine.