English

Timeline

Top Qs

Chat

AI tools

Chat

Top Qs

Timeline

Loading AI tools

Wrch1

G protein From Wikipedia, the free encyclopedia

Wikiwand ❤️ Wikipedia

Edit in Wikipedia Revision history Read in Wikipedia

Wikiwand in your browser!

Seamless Wikipedia browsing. On steroids.

Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.

Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.

Wikiwand for Chrome

Wikiwand for Firefox

RhoU (or Wrch1 or Chp2) is a small (~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rho family of GTPases. Wrch1 was identified in 2001 as encoded by a non-canonical Wnt induced gene.^[1] RhoU/Wrch delineates with RhoV/Chp a Rho subclass related to Rac and Cdc42, which emerged in early multicellular organisms during evolution.^[2]

References

[1]
Tao W, Pennica D, Xu L, Kalejta RF, Levine AJ (2001). "Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1". Genes Dev. 15 (14): 1796–807. doi:10.1101/gad.894301. ISSN 0890-9369. PMC 312736. PMID 11459829.
[2]
Boureux A, Vignal E, Faure S, Fort P (2007). "Evolution of the Rho family of ras-like GTPases in eukaryotes". Mol Biol Evol. 24 (1): 203–16. doi:10.1093/molbev/msl145. ISSN 0021-9193. PMC 2665304. PMID 17035353.

Biology

This protein-related article is a stub. You can help Wikipedia by expanding it.

v
t
e