Ziconotide
Drug for chronic pain / From Wikipedia, the free encyclopedia
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Ziconotide, sold under the brand name Prialt, also called intrathecal ziconotide (ITZ) because of its administration route, is an atypical analgesic agent for the amelioration of severe and chronic pain. Derived from Conus magus, a cone snail, it is the synthetic form of an ω-conotoxin peptide.[1] It is 1,000 times as powerful as morphine.[citation needed]
Quick Facts Clinical data, Pronunciation ...
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Pronunciation | /zaɪˈkɒnoʊtaɪd/ zy-KON-oh-tyd |
Other names | SNX–111 |
AHFS/Drugs.com | Monograph |
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Routes of administration | Intrathecal – directly into cerebrospinal fluid by a catheter |
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Bioavailability | 50% |
Elimination half-life | 2.9 to 6.5 hours |
Excretion | <1% urine |
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ECHA InfoCard | 100.212.174 |
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Formula | C102H172N36O32S7 |
Molar mass | 2639.14 g·mol−1 |
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In December 2004 the Food and Drug Administration approved ziconotide when delivered as an infusion into the cerebrospinal fluid using an intrathecal pump system.