(+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)

(+)-α-Santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) (EC 4.2.3.50, SBS) is an enzyme with systematic name (2Z,6Z)-farnesyl diphosphate lyase (cyclizing; (+)-α-santalene-forming).^[1] This enzyme catalyses the following chemical reaction

(2Z,6Z)-farnesyl diphosphate ${\displaystyle \rightleftharpoons }$ (+)-α-santalene + diphosphate

(+)-α-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)
Identifiers
EC no.	4.2.3.50
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-farnesyl diphosphate.