(2Z,6Z)-farnesyl diphosphate synthase

(2Z,6Z)-farnesyl diphosphate synthase (EC 2.5.1.92, cis,cis-farnesyl diphosphate synthase, Z,Z-FPP synthase, zFPS, Z,Z-farnesyl pyrophosphate synthase) is an enzyme with systematic name dimethylallyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 2 isopentenyl units).^[1] This enzyme catalyses the following chemical reaction

dimethylallyl diphosphate + 2 isopentenyl diphosphate ${\displaystyle \rightleftharpoons }$ 2 diphosphate + (2Z,6Z)-farnesyl diphosphate

(2Z,6Z)-farnesyl diphosphate synthase
Identifiers
EC no.	2.5.1.92
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
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This enzyme was originally characterized from the wild hairy tomato Solanum habrochaites.