(R)-citramalate synthase

(R)-citramalate synthase (EC 2.3.1.182, CimA) is an enzyme.^[1][2] This enzyme catalyses the following chemical reaction

acetyl-CoA + pyruvate + H₂O ${\displaystyle \rightleftharpoons }$ CoA + (2R)-2-hydroxy-2-methylbutanedioate

(R)-citramalate synthase
Identifiers
EC no.	2.3.1.182
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

This enzyme participates in a novel pyruvate pathway for isoleucine biosynthesis.