1-Deoxy-D-xylulose 5-phosphate

1-Deoxy-d-xylulose 5-phosphate is a biosynthetic intermediate in the non-mevalonate pathway.^[1]

1-Deoxy-d-xylulose 5-phosphate

Names
IUPAC name (2,3-dihydroxy-4-oxopentyl) dihydrogen phosphate
Other names DOXP
Identifiers
CAS Number	190079-18-6 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:16493 Y
ChemSpider	391473 Y
DrugBank	DB02496 Y
KEGG	C11437 Y
MeSH	1-deoxy-D-xylulose+5-phosphate
PubChem CID	443201
UNII	I4C288B3TN Y
CompTox Dashboard (EPA)	DTXSID90940547
InChI InChI=1S/C5H11O7P/c1-3(6)5(8)4(7)2-12-13(9,10)11/h4-5,7-8H,2H2,1H3,(H2,9,10,11)/t4-,5-/m1/s1 Y Key: AJPADPZSRRUGHI-RFZPGFLSSA-N Y InChI=1/C5H11O7P/c1-3(6)5(8)4(7)2-12-13(9,10)11/h4-5,7-8H,2H2,1H3,(H2,9,10,11)/t4-,5-/m1/s1 Key: AJPADPZSRRUGHI-RFZPGFLSBQ
SMILES O=P(O)(O)OC[C@@H](O)[C@H](O)C(=O)C
Properties
Chemical formula	C5H11O7P
Molar mass	214.11
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Function

The enzyme involved in making 1-deoxy-d-xylulose 5-phosphate (DXP) is DXP synthase.^[2] The mechanism follows a catalysis of decarboxylative condensation of pyruvate and d-glyceraldehyde 3-phosphate to produce DXP.^[2][3] In addition, the molecule is involved in making thiamine (vitamin B₁) and pyridoxol (vitamin B₆).^[2]

The non-mevalonate pathway intermediate 1-deoxy-d-xylulose 5-phosphate (DXP) also acts as a precursor in making isoprenoids in many species such as bacteria, plants, and apicomplexan parasites, contributing to biological diversity.^[1]

See also

• DXP reductoisomerase
• Terpenoid