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2,3-Dimethylphenylpiperazine

Pharmaceutical compound From Wikipedia, the free encyclopedia

2,3-Dimethylphenylpiperazine
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2,3-Dimethylphenylpiperazine (2,3-DMPP; code name PAL-218) is a monoamine releasing agent and designer drug of the phenylpiperazine family.[1][2][3][4] It acts as a partial serotonin–norepinephrine releasing agent (SNRA), with EC50Tooltip half-maximal effective concentration (EmaxTooltip maximal efficacy) values of 24 to 26 nM (85%) for serotonin, 13.7 to 56 nM (62%) for norepinephrine, and 1,207 to 1,320 nM (66%) for dopamine (22–96-fold lower than serotonin and norepinephrine).[1][2] Its possible activities at serotonin receptors were not reported.[1][2] The drug was first described in the scientific literature by 2009.[3][1][2]

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