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2,5-Dimethoxy-4-acetylamphetamine

Pharmaceutical compound From Wikipedia, the free encyclopedia

2,5-Dimethoxy-4-acetylamphetamine
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2,5-Dimethoxy-4-acetylamphetamine (DOAc) is a serotonin 5-HT2 receptor modulator of the amphetamine and DOx families.[1] Its affinities (Ki) for the human serotonin 5-HT2 receptors are 80.5 nM for the serotonin 5-HT2A receptor, 313 nM for the serotonin 5-HT2B receptor, and 91.3 nM for the serotonin 5-HT2C receptor.[1] These affinities are much lower than those of many other DOx derivatives, such as DOB, but are very similar to those of 3,4,5-trimethoxyamphetamine (TMA).[1]

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