Top Qs
Timeline
Chat
Perspective

2,5-didehydrogluconate reductase

Class of enzymes From Wikipedia, the free encyclopedia

Remove ads

In enzymology, a 2,5-didehydrogluconate reductase (EC 1.1.1.274) is an enzyme that catalyzes the chemical reaction

2-dehydro-D-gluconate + NADP+ 2,5-didehydro-D-gluconate + NADPH + H+

Thus, the two substrates of this enzyme are 2-dehydro-D-gluconate and NADP+, whereas its 3 products are 2,5-didehydro-D-gluconate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-dehydro-D-gluconate:NADP+ 2-oxidoreductase. Other names in common use include 2,5-diketo-D-gluconate reductase, and YqhE reductase.

Remove ads

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1VP5.

References

Loading related searches...

Wikiwand - on

Seamless Wikipedia browsing. On steroids.

Remove ads