2-APQC

2-APQC is a drug which acts as a sirtuin-3 (SIRT3) activator. In animal studies, it improved muscle and heart function in aged mice.^[1][2]

2-APQC

Clinical data
Drug class	Sirtuin-3 (SIRT3) activator
Identifiers
IUPAC name 2-amino-1-[(4-fluorophenyl)methyl]-N-pentylpyrrolo[3,2-b]quinoxaline-3-carboxamide
CAS Number	500271-63-6
PubChem CID	1965265
ChemSpider	1499078
Chemical and physical data
Formula	C23H24FN5O
Molar mass	405.477 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCCNC(=O)C1=C(N(C2=NC3=CC=CC=C3N=C12)CC4=CC=C(C=C4)F)N
InChI InChI=1S/C23H24FN5O/c1-2-3-6-13-26-23(30)19-20-22(28-18-8-5-4-7-17(18)27-20)29(21(19)25)14-15-9-11-16(24)12-10-15/h4-5,7-12H,2-3,6,13-14,25H2,1H3,(H,26,30) Key:FYNPHMNXVLLDAS-UHFFFAOYSA-N