2-Oxohistidine

2-Oxohistidine is a derivative of histidine damaged by reactive oxygen species. It is a biological marker for assessing protein modifications from oxidative stress.^[1] In particular, it arises by iron-catalyzed reaction with hydrogen peroxide.^[2]

2-Oxohistidine

Names
IUPAC name 3-(2-Oxo-2H-imidazol-4-yl)alanine
Identifiers
CAS Number	181996-08-7
3D model (JSmol)	Interactive image
ChemSpider	19981749
PubChem CID	127761
CompTox Dashboard (EPA)	DTXSID20934257
InChI InChI=1S/C6H7N3O3/c7-4(5(10)11)1-3-2-8-6(12)9-3/h2,4H,1,7H2,(H,10,11) COPY Key: MWUSZYAURGSGRY-UHFFFAOYSA-N
SMILES C1=NC(=O)N=C1CC(C(=O)O)N
Properties
Chemical formula	C6H7N3O3
Molar mass	169.140 g·mol−1
Appearance	white solid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references