2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase (EC 2.2.1.10, ADH synthase, ADHS, MJ0400 (gene)) is an enzyme with systematic name L-aspartate 4-semialdehyde:1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate methylglyoxaltransferase.^[1][2][3] This enzyme catalyses the following chemical reaction

L-aspartate 4-semialdehyde + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate ${\displaystyle \rightleftharpoons }$ 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + 2,3-dioxopropyl phosphate

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase
Identifiers
EC no.	2.2.1.10
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate.