2-Pyrrolylethylamine

2-Pyrrolylethylamine
Clinical data
Other names	2-(2-Pyrrolyl)ethylamine; NEA; 2-NEA
Identifiers
	IUPAC name 2-(1H-pyrrol-2-yl)ethanamine;
CAS Number	40808-62-6;
PubChem CID	13437360;
ChemSpider	13937234;
CompTox Dashboard (EPA)	DTXSID20540817 ;
Chemical and physical data
Formula	C6H10N2
Molar mass	110.160 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1=CNC(=C1)CCN;
	InChI InChI=1S/C6H10N2/c7-4-3-6-2-1-5-8-6/h1-2,5,8H,3-4,7H2; Key:IAZZNTYMXXEHHT-UHFFFAOYSA-N;

2-Pyrrolylethylamine (NEA, 2-NEA, or 2-(2-pyrrolyl)ethylamine) is a chemical compound of the arylalkylamine family.^[1]

Quick Facts Clinical data, Other names ...

It is related to other arylalkylamines as well as trace amines including tryptamine (2-indolylethylamine), phenethylamine (2-phenylethylamine), 2-furylethylamine, thiopropamine (1-(2-thienyl)-2-aminopropane), and isocyclamine (cyclopentanylaminopropane), among others.^[1] Many of these compounds are monoamine releasing agents and/or reuptake inhibitors.^[1]

NEA is known to be pharmacologically active itself, for instance having histamine-like activity on the isolated guinea pig ileum and having effects on gastric acid secretion in dogs.^[1]

The compound was first described in the scientific literature by 1949.^[1]

See also