2010–11 Maltese Second and Third Division Knock-Out

The 2010–11 Second and Third Division Knock-Out (known as quick Keno Second and Third Division Knock-Out for sponsorship reasons) was a knockout tournament for Maltese football clubs playing in the Second and Third Division. Played between 1 September 2010 and 8 May 2011, Żejtun Corinthians successfully defended last season's title.

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Pos	Team	Pld	W	D	L	GF	GA	GD	Pts	Qualification	RBT	MDN	MLĦ	GXQ
1	Rabat Ajax	3	2	1	0	5	2	+3	7	Advance to knockout phase	—	2–1	0–0	2–1
2	Mdina Knights	3	1	1	1	3	3	0	4			—	0–0	2–0
3	Mellieħa	3	0	3	0	2	2	0	3				—	2–2
4	Għaxaq	3	0	1	2	3	6	−3	1					—

Pos	Team	Pld	W	D	L	GF	GA	GD	Pts	Qualification	ŻTN	GŻR	GDJ	SLC
1	Żejtun Corinthians	3	3	0	0	6	1	+5	9	Advance to knockout phase	—	2–1	2–0	2–0
2	Gżira United	3	1	1	1	5	3	+2	4			—	4–1	0–0
3	Gudja United	3	1	0	2	3	6	−3	3				—	2–0
4	St. Lucia	3	0	1	2	0	4	−4	1					—

Pos	Team	Pld	W	D	L	GF	GA	GD	Pts	Qualification	MĠR	SĠN	MRS	FGR
1	Mġarr United	3	3	0	0	8	2	+6	9	Advance to knockout phase	—	3–1	2–0	3–1
2	San Ġwann	3	1	1	1	5	5	0	4			—	2–2	2–0
3	Marsa	3	0	2	1	4	6	−2	2				—	2–2
4	Fgura United	3	0	1	2	3	7	−4	1					—

Pos	Team	Pld	W	L	GF	GA	GD	Pts	Qualification	BBĠ	ŻBĠ	SĠW	PBK
1	Birżebbuġa St. Peter's	3	2	1	6	4	+2	6	Advance to knockout phase	—	2–0	2–4	2–0
2	Żebbuġ Rangers	3	2	1	5	4	+1	6			—	1–0	4–2
3	Siġġiewi	3	1	2	5	5	0	3				—	1–2
4	Pembroke Athleta	3	1	2	4	7	−3	3					—

Pos	Team	Pld	W	D	L	GF	GA	GD	Pts	Qualification	MTF	QRD	ŻRQ	MSK
1	Mtarfa	3	2	1	0	3	0	+3	7	Advance to knockout phase	—	0–0	1–0	2–0
2	Qrendi	3	1	2	0	1	0	+1	5			—	0–0	1–0
3	Żurrieq	3	1	1	1	7	1	+6	4				—	7–0
4	Marsaskala	3	0	0	3	0	10	−10	0					—

Group stage