23S rRNA pseudouridine746 synthase

23S rRNA pseudouridine⁷⁴⁶ synthase (EC 5.4.99.29, RluA, 23S RNA PSI⁷⁴⁶ synthase, 23S rRNA pseudouridine synthase, pseudouridine synthase RluA) is an enzyme with systematic name 23S rRNA-uridine⁷⁴⁶ uracil mutase.^[1][2][3] This enzyme catalyses the following chemical reaction

23S rRNA uridine⁷⁴⁶ ${\displaystyle \rightleftharpoons }$ 23S rRNA pseudouridine⁷⁴⁶

23S rRNA pseudouridine746 synthase
Identifiers
EC no.	5.4.99.29
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

RluA is the only protein responsible for the in vivo formation of 23S RNA pseudouridine⁷⁴⁶.