25C-NBOH

25-C-NBOH (2C-C-NBOH, NBOH-2CC) is a derivative of the phenethylamine derived hallucinogen 2C-C which has been sold as a designer drug. It has similar serotonin receptor affinity to the better-known compound 25C-NBOMe.^[2][3]

25C-NBOH

Legal status
Legal status	BR: Class F2 (Prohibited psychotropics)[1] DE: NpSG (Industrial and scientific use only) UK: Class A
Identifiers
IUPAC name 2-({[2-(4-chloro-2,5-dimethoxyphenyl)ethyl]amino}methyl)phenol
CAS Number	1391488-16-6 Y
PubChem CID	125181419
ChemSpider	58191432
UNII	P8BP3X5EBR
Chemical and physical data
Formula	C17H20ClNO3
Molar mass	321.80 g·mol−1
3D model (JSmol)	Interactive image
SMILES COc1cc(Cl)c(OC)cc1CCNCc2ccccc2O
InChI InChI=1S/C17H20ClNO3/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-19-11-13-5-3-4-6-15(13)20/h3-6,9-10,19-20H,7-8,11H2,1-2H3 Key:VHWXICYYQMMZCW-UHFFFAOYSA-N

Analogues and derivatives

• 25C-NBF
• 25C-NBMD
• 25C-NBOH
• 25C-NBOMe (NBOMe-2CC)
• 25C-NB3OMe
• 25C-NB4OMe
• 25I-NBOH
• 25B-NBOH
• 25E-NBOH
• 25H-NBOH

Analytical chemistry

25C-NBOH undergoes degradation under routine Gas Chromatography (GC) conditions, as well as other NBOH's substances, into 2C-C.^[4][5] An alternative method proposed for reliable identification of 25I-NBOH using GC/MS may be used for 25C-NBOH analysis.^[6][7]

Legality

United Kingdom

This substance is a Class A drug in the United Kingdom as a result of the N-benzylphenethylamine catch-all clause in the Misuse of Drugs Act 1971.^[8]