2C-F

2C-F, also known as 4-fluoro-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families.^[1][2] It is taken orally.^[1]

2C-F

Clinical data
Other names	4-Fluoro-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-fluorophenethylamine
Routes of administration	Oral[1]
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Legal status
Legal status	BR: Class F2 (Prohibited psychotropics) CA: Schedule III UK: Class A
Pharmacokinetic data
Onset of action	Unknown[1]
Duration of action	Unknown[1]
Identifiers
IUPAC name 2-(4-fluoro-2,5-dimethoxyphenyl)-1-aminoethane
CAS Number	207740-15-6 Y
PubChem CID	44719499
ChemSpider	21106223 Y
UNII	O01SQJ93TV
CompTox Dashboard (EPA)	DTXSID70660357
Chemical and physical data
Formula	C10H14FNO2
Molar mass	199.225 g·mol−1
3D model (JSmol)	Interactive image
SMILES Fc1cc(OC)c(cc1OC)CCN
InChI InChI=1S/C10H14FNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3 Y Key:QAVFEDRVOUKIPM-UHFFFAOYSA-N Y
(verify)

Use effects

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists the dose of 2C-F as greater than 250 mg orally and its duration as unknown.^[1] At a dose of 250 mg, 2C-F produces slight and uncertain effects including possible modest closed-eye visuals and pleasant lethargy.^[1]

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-F.^[1][3]

Chemistry

Properties

2C-F may be found as a brownish freebase oil, or as a white crystalline hydrochloride salt.

Synthesis

The chemical synthesis of 2C-F has been described.^[1]

Analogues

Analogues of 2C-F include 2C-B, 2C-I, 2C-C, DOF, and 25F-NBOMe, among others.^[1]

History

2C-F was first described in the literature by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).^[1]

Society and culture

Legal status

Canada

As of October 31, 2016, 2C-F is a controlled substance (Schedule III) in Canada.^[4]

See also

• 2C (psychedelics)