2C-G-3

2C-G-3, also known as 2,5-dimethoxy-3,4-(trimethylene)phenethylamine, is a psychedelic drug of the phenethylamine and 2C families.^[1] It is the derivative of 2C-G (2C-G-0) in which the 3,4-dimethyl groups have been connected via an additional carbon atom to form a cyclopentane ring attached to the benzene ring and hence has a dihydroindene ring system.^[1] In his 1991 book PiHKAL (Phenethylamines I Have Known and Loved) and other publications, Alexander Shulgin lists 2C-G-3's dose as 16 to 25 mg orally and its duration as 12 to 24 hours.^[1][2][3] The effects of 2C-G-3 were reported to include "lots of LSD-like sparkles", easier communication, impairment, and social avoidance, among others.^[1] One report remarked that it was "marvelous".^[1] The chemical synthesis of 2C-G-3 has been described.^[1] The drug was first described in the literature by Shulgin in PiHKAL in 1991.^[1]

2C-G-3

Clinical data
Other names	2,5-Dimethoxy-3,4-(trimethylene)phenethylamine; 3,4-Trimethylene-2,5-dimethoxyphenethylamine; 3,4-Trimethylene-2,5-DMPEA
Routes of administration	Oral[1]
Drug class	Serotonergic psychedelic; Hallucinogen
ATC code	None
Pharmacokinetic data
Duration of action	12–24 hours[1]
Identifiers
IUPAC name 2-(4,7-dimethoxy-2,3-dihydro-1H-inden-5-yl)ethanamine
CAS Number	207740-19-0
PubChem CID	44350123
ChemSpider	23206516
UNII	9UT94P2UB5
ChEMBL	ChEMBL341036
CompTox Dashboard (EPA)	DTXSID701016883
Chemical and physical data
Formula	C13H19NO2
Molar mass	221.300 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=C2CCCC2=C(C(=C1)CCN)OC
InChI InChI=1S/C13H19NO2/c1-15-12-8-9(6-7-14)13(16-2)11-5-3-4-10(11)12/h8H,3-7,14H2,1-2H3 Key:DUYSKWSFDDDWQI-UHFFFAOYSA-N

See also

• 2C (psychedelics)
• 2C-G (2C-G-0)
• 2C-G-5 and 2C-G-N
• Ganesha and G-3
• 5-APDI (IAP)