3-Ketosteroid 9alpha-monooxygenase

3-ketosteroid 9alpha-monooxygenase (EC 1.14.13.142, KshAB, 3-ketosteroid 9alpha-hydroxylase) is an enzyme with systematic name androsta-1,4-diene-3,17-dione,NADH:oxygen oxidoreductase (9alpha-hydroxylating).^[1][2][3] This enzyme catalyses the following chemical reaction

androsta-1,4-diene-3,17-dione + NADH + H⁺ + O₂ ${\displaystyle \rightleftharpoons }$ 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD⁺ + H₂O

3-ketosteroid 9alpha-monooxygenase
Identifiers
EC no.	1.14.13.142
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

3-Ketosteroid 9alpha-monooxygenase is involved in the cholesterol degradation in several bacterial pathogens.