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4-Fluoronitrobenzene
Chemical compound From Wikipedia, the free encyclopedia
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4-Fluoronitrobenzene is an organic compound with the formula FC6H4NO2. It is one of three isomeric fluoronitrobenzenes.[2] A yellow oil, it is prepared from 4-nitrochlorobenzene using the Halex process:
- O2NC6H4Cl + KF → O2NC6H4F + KCl
4-Fluoronitrobenzene can be hydrogenated to give 4-fluoroaniline,[3] which is a precursor to the fungicide fluoroimide and parafluorofentanyl.
Owing to the presence of the electron withdrawing nitro group, the fluoride is a good leaving group in fluoronitrobenzenes. Thus reaction with phenoxide gives the mononitrodiphenylether.[4]
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Applications
- U-41792
- B777-81
- WAY-213,613
- Butacetin[5]
References
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