4-Hydroxyphenylacetic acid

4-Hydroxyphenylacetic acid is a chemical compound found in olive oil^[1] and beer.^[2]

4-Hydroxyphenylacetic acid

Chemical structure of 4-hydroxyphenylacetic acid
Names
Preferred IUPAC name (4-Hydroxyphenyl)acetic acid
Other names p-Hydroxyphenylacetic acid
Identifiers
CAS Number	156-38-7 Y
3D model (JSmol)	Interactive image
Beilstein Reference	1448766
ChEBI	CHEBI:18101 Y
ChEMBL	ChEMBL1772 Y
ChemSpider	124 Y
ECHA InfoCard	100.005.321
EC Number	205-851-3
KEGG	C00642 Y
PubChem CID	127
UNII	3J9SHG0RCN Y
CompTox Dashboard (EPA)	DTXSID5059745
InChI InChI=1S/C8H8O3/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4,9H,5H2,(H,10,11) Y Key: XQXPVVBIMDBYFF-UHFFFAOYSA-N Y
SMILES O=C(O)Cc1ccc(O)cc1
Properties
Chemical formula	C8H8O3
Molar mass	152.149 g·mol−1
Appearance	Beige powder
Melting point	150 °C (302 °F; 423 K)
Hazards
Safety data sheet (SDS)	MSDS at Sigma Aldrich
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Synthesis

4-Hydroxyphenylacetic acid is obtained by reducing 4-hydroxymandelic acid with elemental phosphorus and iodine.^[3]

Uses

In industry, 4-hydroxyphenylacetic acid is an intermediate used to synthesize atenolol,^[3] 3,4-dihydroxyphenylacetic acid,^[4] and coclaurine.