4-MeO-DET

4-MeO-DET, also known as 4-methoxy-N,N-diethyltryptamine, is a chemical compound of the tryptamine and 4-methoxytryptamine families related to psilocin (4-HO-DMT).^[1] It is the 4-methoxy derivative of diethyltryptamine (DET), the O-methyl ether 4-HO-DET (ethocin), and a positional isomer of 5-MeO-DET.^[1]

4-MeO-DET

Clinical data
Other names	4-OMe-DET; 4-Methoxy-N,N-diethyltryptamine; 4-Methoxy-DET
Routes of administration	Oral, smoking[1]
ATC code	None
Pharmacokinetic data
Onset of action	Unknown[1]
Duration of action	Unknown[1]
Identifiers
IUPAC name N,N-diethyl-2-(4-methoxy-1H-indol-3-yl)ethanamine
PubChem CID	24802084
ChemSpider	21436170
Chemical and physical data
Formula	C15H22N2O
Molar mass	246.354 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN(CC)CCC1=CNC2=C1C(=CC=C2)OC
InChI InChI=1S/C15H22N2O/c1-4-17(5-2)10-9-12-11-16-13-7-6-8-14(18-3)15(12)13/h6-8,11,16H,4-5,9-10H2,1-3H3 Key:HIVMOHVUFLVCMM-UHFFFAOYSA-N

Use and effects

According to Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved), 4-MeO-DET is completely inactive at doses of up to 30 mg orally or smoked.^[1][2] Hence, its dose range is unknown but greater than 30 mg and its duration is unknown.^[1] Higher doses were not assessed.^[1][2]

Chemistry

Analogues

Analogues of 4-MeO-DET include diethyltryptamine (DET), 4-methoxytryptamine (4-MT or 4-MeO-T), 4-HO-DET (ethocin), 4-AcO-DET (ethacetin), 5-MeO-DET, 4-MeO-DMT, 4-MeO-DiPT, and 4-MeO-MiPT, among others.^[1] 4-MeO-MiPT is known to be active, producing erotic-enhancing effects but little in the way of visuals, whereas 4-MeO-DMT and 4-MeO-DiPT have been found to be active in preclinical research but have not been tested in humans.^[1][3][4][5]

History

Aside from 4-MeO-DET's description in Alexander Shulgin's 1997 book TiHKAL (Tryptamines I Have Known and Loved), 4-MeO-DET does not appear to have been otherwise described in the literature.^[1]

See also

• Substituted tryptamine