Acetryptine

Acetryptine
Clinical data
Other names	W-2965-A; 5-Acetyltryptamine; 5-Acetyl-3-(2-aminoethyl)indole;
Identifiers
	IUPAC name 1-[3-(2-Aminoethyl)-1H-indol-5-yl]ethanone;
CAS Number	3551-18-6;
PubChem CID	20810;
ChemSpider	19586;
UNII	N9VWZ34G5E;
ChEMBL	ChEMBL110317;
CompTox Dashboard (EPA)	DTXSID90189015 ;
Chemical and physical data
Formula	C12H14N2O
Molar mass	202.257 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)C1=CC2=C(C=C1)NC=C2CCN;
	InChI InChI=1S/C12H14N2O/c1-8(15)9-2-3-12-11(6-9)10(4-5-13)7-14-12/h2-3,6-7,14H,4-5,13H2,1H3; Key:RAUGYAOLAMRLLZ-UHFFFAOYSA-N;

Acetryptine (INN; developmental code W-2965-A; also known as 5-acetyltryptamine or 5-AT^[1]) is a drug described as an antihypertensive agent which was never marketed.^[2] Structurally, acetryptine is a substituted tryptamine, and is closely related to other substituted tryptamines like serotonin (5-hydroxytryptamine).^[2] It was developed in the early 1960s.^[2]^[1] The binding of acetryptine to serotonin receptors does not seem to have been well-investigated, although it was assessed at the 5-HT_1A and 5-HT_1D receptors and found to bind to them with high affinity.^[3] The drug may also act as a monoamine oxidase inhibitor (MAOI); specifically, as an inhibitor of MAO-A.^[4]^[5]

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