5-Ethoxy-DMT

5-Ethoxy-DMT, or 5-EtO-DMT, also known as 5-ethoxy-N,N-dimethyltryptamine or as O-ethylbufotenine, is a tryptamine derivative which has been previously synthesized as a chemical intermediate, but has not been studied to determine its pharmacology.^[1]

5-Ethoxy-DMT

Clinical data
Other names	5-EtO-DMT; 5-Ethoxy-N,N-dimethyltryptamine; O-Ethylbufotenine; O-Ethylbufotenin
Identifiers
IUPAC name 2-(5-ethoxy-1H-indol-3-yl)-N,N-dimethylethanamine
CAS Number	855245-09-9 N
PubChem CID	57468316
ChemSpider	26286732 Y
UNII	RXJ4TM3EX4
CompTox Dashboard (EPA)	DTXSID70726745
Chemical and physical data
Formula	C14H20N2O
Molar mass	232.327 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOc(cc12)ccc1[nH]cc2CCN(C)C
InChI InChI=1S/C14H20N2O/c1-4-17-12-5-6-14-13(9-12)11(10-15-14)7-8-16(2)3/h5-6,9-10,15H,4,7-8H2,1-3H3 Y Key:OSUDCFCSUHGWJF-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Chemistry

Analogues

Analogues of 5-EtO-DMT include bufotenin (5-HO-DMT), 5-MeO-DMT (mebufotenin), 5-EtO-AMT, 5-AlO-AMT, 5-ethyl-DMT, 5-NOT, 5-BT, and 4-AcO-DMT (O-acetylbufotenin), among others.

The widespread recreational use of 5-methoxytryptamines including 5-MeO-DMT, 5-MeO-MiPT and 5-MeO-DiPT has led to concern that the 5-ethoxy homologues of these drugs could emerge as novel designer drugs.^[2] Consequently, 5-EtO-DMT and other derivatives, including 5-EtO-DET, 5-EtO-DPT, 5-EtO-DiPT, 5-EtO-DALT, 5-EtO-MPT, 5-EtO-MiPT, 5-EtO-EiPT, 5-EtO-MET, and 5-EtO-EPT, have been synthesized as analytical standards in order to facilitate future research into these compounds.^[2]

See also

• Substituted tryptamine