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5-MeO-AET
Chemical compound From Wikipedia, the free encyclopedia
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5-Methoxy-α-ethyltryptamine (5-MeO-αET) is a psychoactive drug and member of the tryptamine family.[1] It reportedly produces psychedelic and stimulant effects.[1][2]
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Use and dosage
5-MeO-αET, when used recreationally, is usually taken orally at doses of 50 to 75 mg.[1][additional citation(s) needed]
Effects
5-MeO-αET produces entactogenic and stimulant effects that can last 4 to 6 hours.[citation needed] However, little information exists on the psychopharmacological effects of this compound, thus considerable variation with regard to dosage and effects can be expected.[citation needed]
Dangers
There have been no reported deaths or hospitalizations from 5-MeO-αET, but its safety profile is unknown.[citation needed]
Pharmacology
The pharmacology of 5-MeO-αET has been studied.[3] It is a weak partial agonist of the serotonin 5-HT2A receptor, with a binding affinity (Ki) of 4,073 nM, an EC50 of 166 nM, and an Emax of 34%.[3] For comparison, αET showed 14-fold lower affinity for the receptor than 5-MeO-αET and was inactive as an agonist of the receptor.[3] The individual stereoisomers of 5-MeO-αET and αET were also assessed.[3]
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Legal status
5-MeO-αET is unscheduled and uncontrolled in the United States, but possession and sales of 5-MeO-αET could be prosecuted under the Federal Analog Act because of its structural similarities to αET and αMT.
See also
References
External links
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